Neurology

MOG antibody disease (MOGAD)

A recently identified neuro-inflammatory illness called MOG antibody disease (MOGAD) mainly induces inflammation in the optic nerve but can also do so in the spinal cord and brain. The central nervous system's myelin sheaths include a protein called myelin oligodendrocyte glycoprotein (MOG). MOG is a target of the immune system in this condition, despite the fact that the exact function of this glycoprotein is unknown. When patients with recurrent inflammatory episodes of the central nervous system have MOG antibodies in their blood, the diagnosis is established.